Preoperative recombinant human erythropoietin in anemic surgical patients.


Journal Article (Review)

Preoperative anemia in a surgical patient predisposes to poor outcomes and allogeneic blood transfusions. As an alternative to transfusions, pharmacologic management of preoperative anemia with recombinant human erythropoietin (rHuEPO) has been well studied in many different types of surgery. rHuEPO, when used alone or in combination with preoperative autologous blood donation before elective surgery, stimulates erythropoiesis and helps to avoid or reduce the need for allogeneic blood transfusions. The clinical evidence on preoperative use of rHuEPO in orthopedic, cardiac, and cancer surgery, as well as in bloodless surgery, is reviewed.

Full Text

Cited Authors

  • Monk, TG

Published Date

  • January 2004

Published In

Volume / Issue

  • 8 Suppl 2 /

Start / End Page

  • S45 - S48

PubMed ID

  • 15196324

Pubmed Central ID

  • 15196324

Electronic International Standard Serial Number (EISSN)

  • 1466-609X

International Standard Serial Number (ISSN)

  • 1364-8535

Digital Object Identifier (DOI)

  • 10.1186/cc2824


  • eng