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Robust testing of haplotype/disease association.

Publication ,  Journal Article
Allen, AS; Satten, GA
Published in: BMC Genet
December 30, 2005

Haplotypes, the combination of closely linked alleles that fall on the same chromosome, show great promise for studying the genetic components of complex diseases. However, when only multilocus genotype data are available, statistical approaches need to be employed to resolve haplotype phase ambiguity. Recently, we have proposed an approach to testing and estimating haplotype/disease association that is invariant to any existing genetic structure in the population. Here we evaluate this approach by applying it to the Genetic Analysis Workshop 14 simulated data.

Duke Scholars

Published In

BMC Genet

DOI

EISSN

1471-2156

Publication Date

December 30, 2005

Volume

6 Suppl 1

Issue

Suppl 1

Start / End Page

S69

Location

England

Related Subject Headings

  • Humans
  • Haplotypes
  • Genetics & Heredity
  • Genetic Testing
  • Genetic Predisposition to Disease
  • Genetic Loci
  • Disease
  • Bias
  • 3105 Genetics
  • 0604 Genetics
 

Citation

APA
Chicago
ICMJE
MLA
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Allen, A. S., & Satten, G. A. (2005). Robust testing of haplotype/disease association. BMC Genet, 6 Suppl 1(Suppl 1), S69. https://doi.org/10.1186/1471-2156-6-S1-S69
Allen, Andrew S., and Glen A. Satten. “Robust testing of haplotype/disease association.BMC Genet 6 Suppl 1, no. Suppl 1 (December 30, 2005): S69. https://doi.org/10.1186/1471-2156-6-S1-S69.
Allen AS, Satten GA. Robust testing of haplotype/disease association. BMC Genet. 2005 Dec 30;6 Suppl 1(Suppl 1):S69.
Allen, Andrew S., and Glen A. Satten. “Robust testing of haplotype/disease association.BMC Genet, vol. 6 Suppl 1, no. Suppl 1, Dec. 2005, p. S69. Pubmed, doi:10.1186/1471-2156-6-S1-S69.
Allen AS, Satten GA. Robust testing of haplotype/disease association. BMC Genet. 2005 Dec 30;6 Suppl 1(Suppl 1):S69.
Journal cover image

Published In

BMC Genet

DOI

EISSN

1471-2156

Publication Date

December 30, 2005

Volume

6 Suppl 1

Issue

Suppl 1

Start / End Page

S69

Location

England

Related Subject Headings

  • Humans
  • Haplotypes
  • Genetics & Heredity
  • Genetic Testing
  • Genetic Predisposition to Disease
  • Genetic Loci
  • Disease
  • Bias
  • 3105 Genetics
  • 0604 Genetics