Robust testing of haplotype/disease association.
Publication
, Journal Article
Allen, AS; Satten, GA
Published in: BMC Genet
December 30, 2005
Haplotypes, the combination of closely linked alleles that fall on the same chromosome, show great promise for studying the genetic components of complex diseases. However, when only multilocus genotype data are available, statistical approaches need to be employed to resolve haplotype phase ambiguity. Recently, we have proposed an approach to testing and estimating haplotype/disease association that is invariant to any existing genetic structure in the population. Here we evaluate this approach by applying it to the Genetic Analysis Workshop 14 simulated data.
Duke Scholars
Published In
BMC Genet
DOI
EISSN
1471-2156
Publication Date
December 30, 2005
Volume
6 Suppl 1
Issue
Suppl 1
Start / End Page
S69
Location
England
Related Subject Headings
- Humans
- Haplotypes
- Genetics & Heredity
- Genetic Testing
- Genetic Predisposition to Disease
- Genetic Loci
- Disease
- Bias
- 3105 Genetics
- 0604 Genetics
Citation
APA
Chicago
ICMJE
MLA
NLM
Allen, A. S., & Satten, G. A. (2005). Robust testing of haplotype/disease association. BMC Genet, 6 Suppl 1(Suppl 1), S69. https://doi.org/10.1186/1471-2156-6-S1-S69
Allen, Andrew S., and Glen A. Satten. “Robust testing of haplotype/disease association.” BMC Genet 6 Suppl 1, no. Suppl 1 (December 30, 2005): S69. https://doi.org/10.1186/1471-2156-6-S1-S69.
Allen AS, Satten GA. Robust testing of haplotype/disease association. BMC Genet. 2005 Dec 30;6 Suppl 1(Suppl 1):S69.
Allen, Andrew S., and Glen A. Satten. “Robust testing of haplotype/disease association.” BMC Genet, vol. 6 Suppl 1, no. Suppl 1, Dec. 2005, p. S69. Pubmed, doi:10.1186/1471-2156-6-S1-S69.
Allen AS, Satten GA. Robust testing of haplotype/disease association. BMC Genet. 2005 Dec 30;6 Suppl 1(Suppl 1):S69.
Published In
BMC Genet
DOI
EISSN
1471-2156
Publication Date
December 30, 2005
Volume
6 Suppl 1
Issue
Suppl 1
Start / End Page
S69
Location
England
Related Subject Headings
- Humans
- Haplotypes
- Genetics & Heredity
- Genetic Testing
- Genetic Predisposition to Disease
- Genetic Loci
- Disease
- Bias
- 3105 Genetics
- 0604 Genetics