Propagation of fluctuations in biochemical systems, I: linear SSC networks.
Published
Journal Article
We investigate the propagation of random fluctuations through biochemical networks in which the number of molecules of each species is large enough so that the concentrations are well modeled by differential equations. We study the effect of network topology on the emergent properties of the reaction system by characterizing the behavior of variance as fluctuations propagate down chains and studying the effect of side chains and feedback loops. We also investigate the asymptotic behavior of the system as one reaction becomes fast relative to the others.
Full Text
Duke Authors
Cited Authors
- Anderson, DF; Mattingly, JC; Nijhout, HF; Reed, MC
Published Date
- August 2007
Published In
Volume / Issue
- 69 / 6
Start / End Page
- 1791 - 1813
PubMed ID
- 17457656
Pubmed Central ID
- 17457656
Electronic International Standard Serial Number (EISSN)
- 1522-9602
International Standard Serial Number (ISSN)
- 0092-8240
Digital Object Identifier (DOI)
- 10.1007/s11538-007-9192-2
Language
- eng