Genomic medicine: bringing biomarkers to clinical medicine.

Journal Article (Journal Article;Review)

An important by-product of sequencing the human genome has been the development of a novel 'toolbox' for biomarker discovery and development. Genomic medicine is an emerging discipline in the genome sciences that integrates these tools to interrogate genomic variation in well-defined populations in order to develop predictors of disease susceptibility, progression and drug response. Several important classes of biomarkers result from these analyses which, when translated to clinical medicine and drug development, will have an important impact on human health and disease. This review highlights both the opportunities and challenges in bringing biomarkers into clinical medicine.

Full Text

Duke Authors

Cited Authors

  • Seo, D; Ginsburg, GS

Published Date

  • August 2005

Published In

Volume / Issue

  • 9 / 4

Start / End Page

  • 381 - 386

PubMed ID

  • 16006183

International Standard Serial Number (ISSN)

  • 1367-5931

Digital Object Identifier (DOI)

  • 10.1016/j.cbpa.2005.06.009


  • eng

Conference Location

  • England