Integrating diagnostics and therapeutics: revolutionizing drug discovery and patient care.

Journal Article (Journal Article;Review)

Over the next five years it is widely anticipated that the molecular diagnostics industry will continue to grow at double-digit pace to meet increasing demand for personalized medicine. A wide variety of drugs in late preclinical and early clinical development is now being targeted to disease-specific gene and protein defects that will require co-approval of diagnostic and therapeutic products by regulatory agencies. For clinical laboratories and pathologists, this integration of diagnostics and therapeutics represents a major new opportunity to emerge as leaders of the new medicine, guiding the selection, dosage, route of administration and multi-drug combinations, and producing increased efficacy and reduced toxicity of pharmaceutical products.

Full Text

Duke Authors

Cited Authors

  • Ross, JS; Ginsburg, GS

Published Date

  • August 15, 2002

Published In

Volume / Issue

  • 7 / 16

Start / End Page

  • 859 - 864

PubMed ID

  • 12546952

International Standard Serial Number (ISSN)

  • 1359-6446

Digital Object Identifier (DOI)

  • 10.1016/s1359-6446(02)02405-4


  • eng

Conference Location

  • England