Integrating diagnostics and therapeutics: revolutionizing drug discovery and patient care.
Over the next five years it is widely anticipated that the molecular diagnostics industry will continue to grow at double-digit pace to meet increasing demand for personalized medicine. A wide variety of drugs in late preclinical and early clinical development is now being targeted to disease-specific gene and protein defects that will require co-approval of diagnostic and therapeutic products by regulatory agencies. For clinical laboratories and pathologists, this integration of diagnostics and therapeutics represents a major new opportunity to emerge as leaders of the new medicine, guiding the selection, dosage, route of administration and multi-drug combinations, and producing increased efficacy and reduced toxicity of pharmaceutical products.
Duke Scholars
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Related Subject Headings
- Signal Transduction
- Phosphotransferases
- Molecular Biology
- Medicinal & Biomolecular Chemistry
- Humans
- Enzyme Inhibitors
- Animals
- 3214 Pharmacology and pharmaceutical sciences
- 1115 Pharmacology and Pharmaceutical Sciences
- 0601 Biochemistry and Cell Biology
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Signal Transduction
- Phosphotransferases
- Molecular Biology
- Medicinal & Biomolecular Chemistry
- Humans
- Enzyme Inhibitors
- Animals
- 3214 Pharmacology and pharmaceutical sciences
- 1115 Pharmacology and Pharmaceutical Sciences
- 0601 Biochemistry and Cell Biology