Skin and nail changes in children with sickle cell anemia receiving hydroxyurea therapy.
Skin and nail changes from long-term hydroxyurea therapy are reported in adults. Skin and nail changes, including nail hyperpigmentation, longitudinal bands, and hyperpigmentation of the palms and other skin surfaces, developed in 7 children with sickle cell anemia after 6 to 16 weeks of hydroxyurea therapy. Cutaneous and nail changes may occur in children receiving hydroxyurea.
O'branski, EE; Ware, RE; Prose, NS; Kinney, TR
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