Waxy keratoses of childhood in a segmental distribution.

Journal Article (Journal Article)

Waxy keratoses of childhood is a rare genodermatosis previously noted in both familial and isolated presentations. Three previous cases have been described in which the lesions appeared over the trunk and extremities. We report a case in which the waxy keratoses of childhood lesions appeared in a segmental distribution along a single lower extremity, differing from the more extensive patterns reported previously. We suggest a possible postzygotic mutation hypothesis for this unique segmental distribution, addressing both the possibility of a genomic mosaicism and loss of heterozygosity.

Full Text

Duke Authors

Cited Authors

  • Mehrabi, D; Thomas, JE; Selim, MA; Prose, NS

Published Date

  • September 2001

Published In

Volume / Issue

  • 18 / 5

Start / End Page

  • 415 - 416

PubMed ID

  • 11737688

International Standard Serial Number (ISSN)

  • 0736-8046

Digital Object Identifier (DOI)

  • 10.1046/j.1525-1470.2001.01968.x

Language

  • eng

Conference Location

  • United States