Waxy keratoses of childhood in a segmental distribution.
Journal Article (Journal Article)
Waxy keratoses of childhood is a rare genodermatosis previously noted in both familial and isolated presentations. Three previous cases have been described in which the lesions appeared over the trunk and extremities. We report a case in which the waxy keratoses of childhood lesions appeared in a segmental distribution along a single lower extremity, differing from the more extensive patterns reported previously. We suggest a possible postzygotic mutation hypothesis for this unique segmental distribution, addressing both the possibility of a genomic mosaicism and loss of heterozygosity.
Full Text
Duke Authors
Cited Authors
- Mehrabi, D; Thomas, JE; Selim, MA; Prose, NS
Published Date
- September 2001
Published In
Volume / Issue
- 18 / 5
Start / End Page
- 415 - 416
PubMed ID
- 11737688
International Standard Serial Number (ISSN)
- 0736-8046
Digital Object Identifier (DOI)
- 10.1046/j.1525-1470.2001.01968.x
Language
- eng
Conference Location
- United States