Use of bupropion SR in a pharmacist-managed outpatient smoking-cessation program.

Journal Article (Journal Article)

We administered bupropion sustained-release (SR) in a pharmacist-managed outpatient smoking-cessation program. Patients were referred to the program by their primary care physician. All patients completed initial visit questionnaires, received behavioral counseling by a clinical pharmacist, and were provided educational materials on smoking cessation. Seventy-one patients received bupropion SR for treatment of nicotine dependence and were followed for 6 months. Point prevalence abstinence rates were 28.2% and 25.4% at 8 weeks and 6 months, respectively. The trend was toward lower cessation rates in patients with a documented psychiatric diagnosis at 6 months (p=0.064). Bupropion SR was fairly well tolerated, with the most common adverse effects being dry mouth and bad taste. The agent appears to have better success for smoking cessation in patients free of psychiatric comorbidities, but further research is required to support this finding.

Full Text

Duke Authors

Cited Authors

  • Roth, MT; Westman, EC

Published Date

  • May 2001

Published In

Volume / Issue

  • 21 / 5

Start / End Page

  • 636 - 641

PubMed ID

  • 11349752

International Standard Serial Number (ISSN)

  • 0277-0008

Digital Object Identifier (DOI)

  • 10.1592/phco.21.6.636.34548


  • eng

Conference Location

  • United States