Forearm vasoreactivity in type 1diabetic subjects.


Journal Article

This study compared forearm vasoreactivity in 15 Type I diabetic subjects with 15 healthy controls. The groups were matched for age, exercise capacity, and the absence of other cardiovascular risk factors. Vasoreactivity was measured using strain gauge plethysmography, at rest, after arterial occlusion (OCC), and following OCC coupled with handgrip exercise (ROCC). Forearm blood flows were significantly elevated between conditions 2.58 +/- 0.37ml/100mltissue at rest to 26.80 +/- 6.56 after OCC and 32.80 +/- 8.26ml/100mltissue following ROCC in Type I diabetic subjects. There were no differences in forearm blood flow between groups for any of the conditions. These data indicate the degree of forearm blood flow is directly related to the intensity of the vasodilatory stimulus. However, our study did not reveal evidence of impaired vasodilatory capacity in Type I diabetic subjects compared to controls in the absence of other risk factors.

Full Text

Cited Authors

  • Allen, JD; Welsch, M; Aucoin, N; Wood, R; Lee, M; LeBlanc, KE

Published Date

  • February 2001

Published In

Volume / Issue

  • 26 / 1

Start / End Page

  • 34 - 43

PubMed ID

  • 11173668

Pubmed Central ID

  • 11173668

Electronic International Standard Serial Number (EISSN)

  • 1543-2718

International Standard Serial Number (ISSN)

  • 1066-7814

Digital Object Identifier (DOI)

  • 10.1139/h01-003


  • eng