Filling a GAP(DH) in caspase-independent cell death.


Journal Article

Mitochondrial outer-membrane permeabilization can lead to cell death even without activation of caspases. In this issue of Cell, Colell et al. (2007) identify the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase as a potent inhibitor of caspase-independent cell death that may allow metabolically active cells to survive mitochondrial insult.

Full Text

Duke Authors

Cited Authors

  • Rathmell, JC; Kornbluth, S

Published Date

  • June 1, 2007

Published In

Volume / Issue

  • 129 / 5

Start / End Page

  • 861 - 863

PubMed ID

  • 17540167

Pubmed Central ID

  • 17540167

International Standard Serial Number (ISSN)

  • 0092-8674

Digital Object Identifier (DOI)

  • 10.1016/j.cell.2007.05.030


  • eng

Conference Location

  • United States