Self-phase modulation signatures of neuronal activity.

Published

Journal Article

We use phase-sensitive detection of spectral hole refilling to demonstrate strong novel intrinsic nonlinear signatures of neuronal activation in hippocampal brain slices. The ability to gain access to this fundamentally new intrinsic contrast with modest power levels suggests a new approach to in vivo neural imaging. We expect that we can extrapolate our method to high spatial and temporal resolution in deep tissue while retaining the noninvasive character.

Full Text

Published version (via Digital Object Identifier)
Pubmed Central version

Duke Authors

Fischer, Martin
Warren, Warren S.

Cited Authors

Fischer, MC; Liu, HC; Piletic, IR; Escobedo-Lozoya, Y; Yasuda, R; Warren, WS

Published Date

February 2008

Published In

Optics Letters

Volume / Issue

33 / 3

Start / End Page

219 - 221

PubMed ID

18246134

Pubmed Central ID

18246134

Electronic International Standard Serial Number (EISSN)

1539-4794

International Standard Serial Number (ISSN)

0146-9592

Digital Object Identifier (DOI)

10.1364/ol.33.000219

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