Racial variation in initial stroke severity.
Published
Journal Article
BACKGROUND AND PURPOSE: Blacks experience greater morbidity and mortality from stroke than do whites. The degree to which this is due to the severity of the initial stroke is not known. The objective of this study is to determine whether there is a racial difference in initial stroke severity. METHODS: A secondary analysis of a prospective cohort of 984 veterans (29.7% black) admitted to any of 9 geographically diverse Veterans Administration Hospitals for acute stroke between April 1995 and March 1997 was performed. Initial stroke severity was ascertained by using the modified Canadian Neurological Scale (CNS) applied retrospectively to medical record data. Stroke severity, unadjusted and adjusted for covariates, was compared between black and white patients. RESULTS: Blacks had greater initial stroke severity than did whites (mean CNS score 7.96 versus 8.32, respectively; P=0.039), with a 0.5-point difference on the scale corresponding to a single-level decrement in either speech or strength of half of an extremity. This difference persisted with adjustment for other important predictors of stroke severity (P=0. 035). However, there was no significant racial difference in severity when CNS scores were collapsed into a priori clinically relevant categories. CONCLUSIONS: Compared with whites, blacks show greater severity of stroke at hospital admission. It remains uncertain whether the relatively small but significant difference at presentation fully explains the striking racial differences in morbidity and mortality from stroke.
Full Text
Duke Authors
Cited Authors
- Jones, MR; Horner, RD; Edwards, LJ; Hoff, J; Armstrong, SB; Smith-Hammond, CA; Matchar, DB; Oddone, EZ
Published Date
- March 2000
Published In
Volume / Issue
- 31 / 3
Start / End Page
- 563 - 567
PubMed ID
- 10700486
Pubmed Central ID
- 10700486
International Standard Serial Number (ISSN)
- 0039-2499
Digital Object Identifier (DOI)
- 10.1161/01.str.31.3.563
Language
- eng
Conference Location
- United States