Economics of low-molecular weight heparins.

Journal Article (Journal Article;Review)

Low-molecular weight heparins (LMWHs) have become attractive alternatives to standard unfractionated heparin (UFH) for the treatment and prophylaxis of deep vein thrombosis (DVT), and for the management of acute coronary syndrome (ACS). The economic impact of the use of LMWHs has been studied in randomized controlled studies, in demonstration projects in managed care institutions, and in decision models. These studies provide valuable insight into the ways LMWHs can be economically attractive despite higher per unit costs compared with UFH. For the treatment of DVT, the cost benefit of using LMWHs results primarily from the cost shifting from inpatient to outpatient care, and might be limited by the eligibility of patients for outpatient management. In contrast, the attractiveness of LMWHs for ACS and DVT prophylaxis hinges on the increased effectiveness of LMWHs compared with standard UFH.

Full Text

Duke Authors

Cited Authors

  • Rutschmann, OT; Matchar, DB

Published Date

  • November 2000

Published In

Volume / Issue

  • 6 / 20 Suppl

Start / End Page

  • S1054 - S1065

PubMed ID

  • 11484305

International Standard Serial Number (ISSN)

  • 1088-0224


  • eng

Conference Location

  • United States