Superior divisional third cranial nerve paresis: clinical and anatomical observations of 2 unique cases.


Journal Article

BACKGROUND: Within the midbrain, the third nerve nucleus is composed of a complex of subnuclei. The fascicular portion of the nerve courses through the red nucleus and exists in the midbrain just medial to the cerebral peduncle. The cisternal portion of the nerve is a single structure that divides into a superior branch and an inferior branch in the region of the cavernous sinus and superior orbital fissure. OBJECTIVE: To describe 2 patients with superior divisional third cranial nerve paresis resulting from a lesion involving the cisternal portion of the nerve prior to its anatomical bifurcation. PATIENTS: Case 1 was a 77-year-old man with a superior divisional third nerve palsy as the presenting manifestation of a posterior communicating artery aneurysm. Case 2 was a 41-year-old woman who developed a superior divisional third nerve palsy following anterior temporal lobectomy for epilepsy. RESULTS: In both cases, the presumed location of the lesion was the cisternal portion of the third cranial nerve. CONCLUSIONS: Although the anatomical division of the third cranial nerve occurs in the region of the anterior cavernous sinus or superior orbital fissure, there is a topographical arrangement of the motor fibers within the cisternal portion of the nerve. The clinical evaluation of a patient with a third cranial nerve paresis requires an understanding of the regional neuroanatomy and topographical organization of the nerve.

Full Text

Cited Authors

  • Bhatti, MT; Eisenschenk, S; Roper, SN; Guy, JR

Published Date

  • May 2006

Published In

Volume / Issue

  • 63 / 5

Start / End Page

  • 771 - 776

PubMed ID

  • 16682550

Pubmed Central ID

  • 16682550

International Standard Serial Number (ISSN)

  • 0003-9942

Digital Object Identifier (DOI)

  • 10.1001/archneur.63.5.771


  • eng

Conference Location

  • United States