A multiple sclerosis-like illness in a man harboring the mtDNA 14484 mutation.


Journal Article (Review)

In most cases of Leber's hereditary optic neuropathy (LHON) the only clinical manifestation is visual loss. A multiple sclerosis-like illness has been infrequently reported in association with LHON. Most patients are women harboring the mtDNA 11778 mutation. We present a young man with clinical and paraclinical evidence of a demyelinating process with profound bilateral visual loss who harbored the mtDNA 14484 mutation associated with LHON.

Full Text

Cited Authors

  • Bhatti, MT; Newman, NJ

Published Date

  • March 1999

Published In

Volume / Issue

  • 19 / 1

Start / End Page

  • 28 - 33

PubMed ID

  • 10098545

Pubmed Central ID

  • 10098545

International Standard Serial Number (ISSN)

  • 1070-8022


  • eng

Conference Location

  • United States