Psychiatric disorder and quality of life in patients awaiting lung transplantation.

Journal Article (Journal Article)

STUDY OBJECTIVE: To examine the relationship between psychiatric comorbidity and quality of life in patients awaiting lung transplantation. SETTING: Duke University Medical Center/Lung Transplantation Program. PARTICIPANTS: One hundred patients with end-stage pulmonary disease listed for lung transplantation. MEASUREMENTS AND RESULTS: Twenty-five percent (n = 25) of the sample met diagnostic criteria for at least one current mood or anxiety disorder. Controlling for age, gender, ethnicity, percentage of predicted FEV, and lung disease diagnosis, patients with a current psychiatric diagnosis reported poorer general quality of life (p < 0.0001), poorer disease-specific quality of life (p < 0.0001), greater shortness of breath (p = 0.01), more symptoms of psychological distress (p < 0.0001), lower levels of social support (p < 0.0001), and fewer positive health habits (p < 0.04) than their counterparts without a psychiatric diagnosis. CONCLUSIONS: Psychiatric comorbidity affects a significant portion of patients awaiting lung transplantation and is associated with decreased health-related quality of life.

Full Text

Duke Authors

Cited Authors

  • Parekh, PI; Blumenthal, JA; Babyak, MA; Merrill, K; Carney, RM; Davis, RD; Palmer, SM; INSPIRE Investigators,

Published Date

  • November 2003

Published In

Volume / Issue

  • 124 / 5

Start / End Page

  • 1682 - 1688

PubMed ID

  • 14605035

International Standard Serial Number (ISSN)

  • 0012-3692

Digital Object Identifier (DOI)

  • 10.1378/chest.124.5.1682


  • eng

Conference Location

  • United States