Psychiatric disorder and quality of life in patients awaiting lung transplantation.
STUDY OBJECTIVE:To examine the relationship between psychiatric comorbidity and quality of life in patients awaiting lung transplantation. SETTING:Duke University Medical Center/Lung Transplantation Program. PARTICIPANTS:One hundred patients with end-stage pulmonary disease listed for lung transplantation. MEASUREMENTS AND RESULTS:Twenty-five percent (n = 25) of the sample met diagnostic criteria for at least one current mood or anxiety disorder. Controlling for age, gender, ethnicity, percentage of predicted FEV, and lung disease diagnosis, patients with a current psychiatric diagnosis reported poorer general quality of life (p < 0.0001), poorer disease-specific quality of life (p < 0.0001), greater shortness of breath (p = 0.01), more symptoms of psychological distress (p < 0.0001), lower levels of social support (p < 0.0001), and fewer positive health habits (p < 0.04) than their counterparts without a psychiatric diagnosis. CONCLUSIONS:Psychiatric comorbidity affects a significant portion of patients awaiting lung transplantation and is associated with decreased health-related quality of life.
Parekh, PI; Blumenthal, JA; Babyak, MA; Merrill, K; Carney, RM; Davis, RD; Palmer, SM; INSPIRE Investigators,
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