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Memory performance by mild hypertensives following beta-adrenergic blockade.

Publication ,  Journal Article
Madden, DJ; Blumenthal, JA; Ekelund, LG; Krantz, DS; Light, KC; McKee, DC
Published in: Psychopharmacology (Berl)
1986
Published version (DOI) Link to item

Previous experiments have reported deficits in cognitive performance following the administration of beta-adrenoceptor antagonists. These deficits have not appeared consistently, however, and it is not clear from previous studies whether changes in the central nervous system, rather than end-organ functioning, are responsible. The present experiment investigated the effects of beta blockade in a memory-search paradigm that distinguished the relatively central process of memory comparison from the more peripheral processes of stimulus encoding and response selection. Twenty-six adult men with mild essential hypertension received either a placebo or a beta blocker (atenolol or propranolol) for 2 weeks. Although beta blockade did occur in the active drug groups, there were no significant effects of the drugs on memory-search performance.

Duke Scholars

David Joseph Madden
Author David Joseph Madden Psychiatry & Behavioral Sciences, Behavioral Medicine & Neur ...
James Alan Blumenthal
Author James Alan Blumenthal Psychiatry & Behavioral Sciences, Behavioral Medicine & Neur ...

Published In

Psychopharmacology (Berl)

DOI

10.1007/BF00175183

ISSN

0033-3158

Publication Date

1986

Volume

89

Issue

1

Start / End Page

20 / 24

Location

Germany

Related Subject Headings

  • Reaction Time
  • Random Allocation
  • Psychomotor Disorders
  • Psychiatry
  • Propranolol
  • Middle Aged
  • Memory Disorders
  • Male
  • Hypertension
  • Humans
 

Citation

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Chicago
ICMJE
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Madden, D. J., Blumenthal, J. A., Ekelund, L. G., Krantz, D. S., Light, K. C., & McKee, D. C. (1986). Memory performance by mild hypertensives following beta-adrenergic blockade. Psychopharmacology (Berl), 89(1), 20–24. https://doi.org/10.1007/BF00175183
Madden, D. J., J. A. Blumenthal, L. G. Ekelund, D. S. Krantz, K. C. Light, and D. C. McKee. “Memory performance by mild hypertensives following beta-adrenergic blockade.” Psychopharmacology (Berl) 89, no. 1 (1986): 20–24. https://doi.org/10.1007/BF00175183.
Madden DJ, Blumenthal JA, Ekelund LG, Krantz DS, Light KC, McKee DC. Memory performance by mild hypertensives following beta-adrenergic blockade. Psychopharmacology (Berl). 1986;89(1):20–4.
Madden, D. J., et al. “Memory performance by mild hypertensives following beta-adrenergic blockade.” Psychopharmacology (Berl), vol. 89, no. 1, 1986, pp. 20–24. Pubmed, doi:10.1007/BF00175183.
Madden DJ, Blumenthal JA, Ekelund LG, Krantz DS, Light KC, McKee DC. Memory performance by mild hypertensives following beta-adrenergic blockade. Psychopharmacology (Berl). 1986;89(1):20–24.
Journal cover image

Published In

Psychopharmacology (Berl)

DOI

10.1007/BF00175183

ISSN

0033-3158

Publication Date

1986

Volume

89

Issue

1

Start / End Page

20 / 24

Location

Germany

Related Subject Headings

  • Reaction Time
  • Random Allocation
  • Psychomotor Disorders
  • Psychiatry
  • Propranolol
  • Middle Aged
  • Memory Disorders
  • Male
  • Hypertension
  • Humans