Memory performance by mild hypertensives following beta-adrenergic blockade.
Journal Article
Previous experiments have reported deficits in cognitive performance following the administration of beta-adrenoceptor antagonists. These deficits have not appeared consistently, however, and it is not clear from previous studies whether changes in the central nervous system, rather than end-organ functioning, are responsible. The present experiment investigated the effects of beta blockade in a memory-search paradigm that distinguished the relatively central process of memory comparison from the more peripheral processes of stimulus encoding and response selection. Twenty-six adult men with mild essential hypertension received either a placebo or a beta blocker (atenolol or propranolol) for 2 weeks. Although beta blockade did occur in the active drug groups, there were no significant effects of the drugs on memory-search performance.
Full Text
Duke Authors
Cited Authors
- Madden, DJ; Blumenthal, JA; Ekelund, LG; Krantz, DS; Light, KC; McKee, DC
Published Date
- 1986
Published In
Volume / Issue
- 89 / 1
Start / End Page
- 20 - 24
PubMed ID
- 3090588
Pubmed Central ID
- 3090588
International Standard Serial Number (ISSN)
- 0033-3158
Digital Object Identifier (DOI)
- 10.1007/BF00175183
Language
- eng
Conference Location
- Germany