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Effects of exercise and weight loss on mental stress-induced cardiovascular responses in individuals with high blood pressure.

Publication ,  Journal Article
Georgiades, A; Sherwood, A; Gullette, EC; Babyak, MA; Hinderliter, A; Waugh, R; Tweedy, D; Craighead, L; Bloomer, R; Blumenthal, JA
Published in: Hypertension
August 2000

The purpose of this study was to determine the effects of exercise and weight loss on cardiovascular responses during mental stress in mildly to moderately overweight patients with elevated blood pressure. Ninety-nine men and women with high normal or unmedicated stage 1 to stage 2 hypertension (systolic blood pressure 130 to 179 mm Hg, diastolic blood pressure 85 to 109 mm Hg) underwent a battery of mental stress tests, including simulated public speaking, anger recall interview, mirror trace, and cold pressor, before and after a 6-month treatment program. Subjects were randomly assigned to 1 of 3 treatments: (1) aerobic exercise, (2) weight management combining aerobic exercise with a behavioral weight loss program, or (3) waiting list control group. After 6 months, compared with control subjects, participants in both active treatment groups had lower levels of systolic blood pressure, diastolic blood pressure, total peripheral resistance, and heart rate at rest and during mental stress. Compared with subjects in the control group, subjects in the exercise and weight management groups also had greater resting stroke volume and cardiac output. Diastolic blood pressure was lower for the weight management group than for the exercise-only group during all mental stress tasks. These results demonstrate that exercise, particularly when combined with a weight loss program, can lower both resting and stress-induced blood pressure levels and produce a favorable hemodynamic pattern resembling that targeted for antihypertensive therapy.

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Published In

Hypertension

DOI

ISSN

0194-911X

Publication Date

August 2000

Volume

36

Issue

2

Start / End Page

171 / 176

Location

United States

Related Subject Headings

  • Weight Loss
  • Vascular Resistance
  • Systole
  • Stroke Volume
  • Stress, Psychological
  • Physical Fitness
  • Middle Aged
  • Male
  • Humans
  • Hemodynamics
 

Citation

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Georgiades, A., Sherwood, A., Gullette, E. C., Babyak, M. A., Hinderliter, A., Waugh, R., … Blumenthal, J. A. (2000). Effects of exercise and weight loss on mental stress-induced cardiovascular responses in individuals with high blood pressure. Hypertension, 36(2), 171–176. https://doi.org/10.1161/01.hyp.36.2.171
Georgiades, A., A. Sherwood, E. C. Gullette, M. A. Babyak, A. Hinderliter, R. Waugh, D. Tweedy, L. Craighead, R. Bloomer, and J. A. Blumenthal. “Effects of exercise and weight loss on mental stress-induced cardiovascular responses in individuals with high blood pressure.Hypertension 36, no. 2 (August 2000): 171–76. https://doi.org/10.1161/01.hyp.36.2.171.
Georgiades A, Sherwood A, Gullette EC, Babyak MA, Hinderliter A, Waugh R, et al. Effects of exercise and weight loss on mental stress-induced cardiovascular responses in individuals with high blood pressure. Hypertension. 2000 Aug;36(2):171–6.
Georgiades, A., et al. “Effects of exercise and weight loss on mental stress-induced cardiovascular responses in individuals with high blood pressure.Hypertension, vol. 36, no. 2, Aug. 2000, pp. 171–76. Pubmed, doi:10.1161/01.hyp.36.2.171.
Georgiades A, Sherwood A, Gullette EC, Babyak MA, Hinderliter A, Waugh R, Tweedy D, Craighead L, Bloomer R, Blumenthal JA. Effects of exercise and weight loss on mental stress-induced cardiovascular responses in individuals with high blood pressure. Hypertension. 2000 Aug;36(2):171–176.

Published In

Hypertension

DOI

ISSN

0194-911X

Publication Date

August 2000

Volume

36

Issue

2

Start / End Page

171 / 176

Location

United States

Related Subject Headings

  • Weight Loss
  • Vascular Resistance
  • Systole
  • Stroke Volume
  • Stress, Psychological
  • Physical Fitness
  • Middle Aged
  • Male
  • Humans
  • Hemodynamics