Failure of exercise to reduce blood pressure in patients with mild hypertension. Results of a randomized controlled trial.


Journal Article

--To assess the effects of physical exercise training on blood pressure in patients with mild hypertension.--Randomized controlled trial.--Hospital-based cardiac rehabilitation program.--Ninety-nine men and women with untreated mild hypertension (systolic blood pressure, 140 to 180 mm Hg; diastolic blood pressure, 90 to 105 mm Hg) were included in the volunteer sample.--Subjects were randomly assigned to a 4-month program of aerobic exercise training, strength and flexibility training, or to a waiting list control group.--The main outcome measures were systolic and diastolic blood pressures measured four times with a random zero sphygmomanometer on 3 separate days in a clinic setting.--After 4 months of exercise training, subjects in the aerobic exercise group did not exhibit greater reductions in blood pressure than subjects in the control group. We expected a differential decline of 5 mm Hg between the aerobic exercise and waiting list control groups and found a difference of -1.0 +/- 16 mm Hg and -1.2 +/- 10 mm Hg at alpha = .05 for systolic and diastolic blood pressure, respectively.--Moderate aerobic exercise alone should not be considered a replacement for pharmacologic therapy in nonobese patients with mild hypertension.

Full Text

Duke Authors

Cited Authors

  • Blumenthal, JA; Siegel, WC; Appelbaum, M

Published Date

  • October 1991

Published In

Volume / Issue

  • 266 / 15

Start / End Page

  • 2098 - 2104

PubMed ID

  • 1920698

Pubmed Central ID

  • 1920698

Electronic International Standard Serial Number (EISSN)

  • 1538-3598

International Standard Serial Number (ISSN)

  • 0098-7484

Digital Object Identifier (DOI)

  • 10.1001/jama.266.15.2098


  • eng