Adverse reaction characterized by chest pain, shortness of breath, and syncope associated with verteporfin (visudyne).
Journal Article (Journal Article)
PURPOSE: To report a serious adverse reaction associated with verteporfin infusion. DESIGN: Observational case report. METHODS: Case report of a single individual undergoing photodynamic therapy (PDT) with verteporfin. RESULTS: A 77-year-old man with long-standing asymptomatic atrial fibrillation, but no known coronary artery disease experienced severe chest and neck pain, shortness of breath, and syncope while undergoing a fourth photodynamic therapy (PDT) treatment with verteporfin. This infusion had been preceded by three prior infusions; the first two were uneventful, and the third was associated with milder, but similar symptoms. Evaluation demonstrated that the chest pain was noncardiac in origin. CONCLUSION: As verteporfin continues to be used around the world, physicians must be alert to the possibility of serious adverse side effects associated with its use.
Full Text
Duke Authors
Cited Authors
- Cahill, MT; Smith, BT; Fekrat, S
Published Date
- August 2002
Published In
Volume / Issue
- 134 / 2
Start / End Page
- 281 - 282
PubMed ID
- 12140044
International Standard Serial Number (ISSN)
- 0002-9394
Digital Object Identifier (DOI)
- 10.1016/s0002-9394(02)01475-7
Language
- eng
Conference Location
- United States