Group 2A idiopathic juxtafoveolar retinal telangiectasia in monozygotic twins.

Published

Journal Article

PURPOSE: To report the clinical and fluorescein angiographic characteristics of monozygotic twins affected by group 2A idiopathic juxtafoveolar retinal telangiectasia. DESIGN: Observational case report. METHODS: Both eyes of identical twins were examined in a clinical practice setting. RESULTS: Two 68-year-old Caucasian, monozygotic, female twins were examined. In one twin, visual acuity was 20/50 in the right eye (OD) and 20/40 in the left (OS). Ophthalmoscopy demonstrated right-angle venules without edema in both eyes (OU). Fluorescein angiography demonstrated areas of leakage temporal to the fovea OU with some nasal leakage OS. In her identical twin sister, with type II diabetes, visual acuity was 20/60 OD and 20/25 OS. Right-angle venules OU, refractile deposits OS, and no macular edema OU were present. Fluorescein angiography demonstrated areas of parafoveal leakage temporal and nasal OD and temporal OS. CONCLUSION: This is the second set of female monozygotic twins with group 2A idiopathic juxtafoveolar retinal telangiectasia reported in the literature. This finding suggests a genetic component in the pathogenesis of this retinal vascular disease.

Full Text

Duke Authors

Cited Authors

  • Siddiqui, N; Fekrat, S

Published Date

  • March 2005

Published In

Volume / Issue

  • 139 / 3

Start / End Page

  • 568 - 570

PubMed ID

  • 15767084

Pubmed Central ID

  • 15767084

International Standard Serial Number (ISSN)

  • 0002-9394

Digital Object Identifier (DOI)

  • 10.1016/j.ajo.2004.09.030

Language

  • eng

Conference Location

  • United States