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Clinicopathologic correlation of an epiretinal membrane associated with a recurrent macular hole.

Publication ,  Journal Article
Fekrat, S; Wendel, RT; de la Cruz, Z; Green, WR
Published in: Retina
1995

PURPOSE: To describe the clinicopathologic features of an epiretinal membrane associated with a recurrent, full-thickness idiopathic macular hole and speculate on the mechanism(s) contributing to its recurrence 1 year after initially successful closure of pars plana vitrectomy and gas tamponade (SF6). METHODS: After fixation of the 2 x 1 mm specimen in a mixture of 1% glutaraldehyde and 4% formaldehyde followed by 2.5% glutaraldehyde, postfixation with osmium tetroxide, and standard dehydration, the specimen was embedded in epoxy resin. Ultrathin sections were stained with uranyl acetate and lead citrate for transmission electron microscopy. RESULTS: Ultrastructural examination disclosed a fibrocellular membrane composed of Müller cells and fibrous astrocytes. Native collagen was entrapped in the matrix in some areas. CONCLUSION: Those cells that may lead to the closure of an idiopathic macular hole may also contribute to its recurrence if the reparative process goes awry.

Duke Scholars

Published In

Retina

DOI

ISSN

0275-004X

Publication Date

1995

Volume

15

Issue

1

Start / End Page

53 / 57

Location

United States

Related Subject Headings

  • Vitrectomy
  • Visual Acuity
  • Sulfur Hexafluoride
  • Retinal Perforations
  • Retina
  • Recurrence
  • Ophthalmology & Optometry
  • Middle Aged
  • Humans
  • Fundus Oculi
 

Citation

APA
Chicago
ICMJE
MLA
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Fekrat, S., Wendel, R. T., de la Cruz, Z., & Green, W. R. (1995). Clinicopathologic correlation of an epiretinal membrane associated with a recurrent macular hole. Retina, 15(1), 53–57. https://doi.org/10.1097/00006982-199515010-00010
Fekrat, S., R. T. Wendel, Z. de la Cruz, and W. R. Green. “Clinicopathologic correlation of an epiretinal membrane associated with a recurrent macular hole.Retina 15, no. 1 (1995): 53–57. https://doi.org/10.1097/00006982-199515010-00010.
Fekrat S, Wendel RT, de la Cruz Z, Green WR. Clinicopathologic correlation of an epiretinal membrane associated with a recurrent macular hole. Retina. 1995;15(1):53–7.
Fekrat, S., et al. “Clinicopathologic correlation of an epiretinal membrane associated with a recurrent macular hole.Retina, vol. 15, no. 1, 1995, pp. 53–57. Pubmed, doi:10.1097/00006982-199515010-00010.
Fekrat S, Wendel RT, de la Cruz Z, Green WR. Clinicopathologic correlation of an epiretinal membrane associated with a recurrent macular hole. Retina. 1995;15(1):53–57.

Published In

Retina

DOI

ISSN

0275-004X

Publication Date

1995

Volume

15

Issue

1

Start / End Page

53 / 57

Location

United States

Related Subject Headings

  • Vitrectomy
  • Visual Acuity
  • Sulfur Hexafluoride
  • Retinal Perforations
  • Retina
  • Recurrence
  • Ophthalmology & Optometry
  • Middle Aged
  • Humans
  • Fundus Oculi