Intravitreal tissue plasminogen activator for the treatment of central retinal vein occlusion.


Journal Article

A 58-year-old hypertensive man with a perfused central retinal vein occlusion of 21 days' duration received 50 microg of intravitreal recombinant tissue plasminogen activator in 0.1 cc. Best-corrected visual acuity improved 2 weeks after the injection. Optical coherence tomography and fluorescein angiography demonstrated resolution of cystoid macular edema and improvement of venous outflow. Intravitreal tissue plasminogen activator may be a useful treatment for central retinal vein occlusion with a duration of 21 days or less.

Full Text

Duke Authors

Cited Authors

  • Weizer, JS; Fekrat, S

Published Date

  • July 2003

Published In

Volume / Issue

  • 34 / 4

Start / End Page

  • 350 - 352

PubMed ID

  • 12875471

Pubmed Central ID

  • 12875471

International Standard Serial Number (ISSN)

  • 1542-8877


  • eng

Conference Location

  • United States