Current perspectives on locally advanced pancreatic cancer.


Journal Article (Review)

This year, approximately 40% of the 28,300 patients diagnosed with pancreatic carcinoma in the United States will present with locally advanced disease. Radiotherapeutic approaches are often employed, as these patients have unresectable tumors by virtue of local invasion into the retroperitoneal vessels in the absence of clinically detectable metastases. These treatments include external-beam irradiation with and without fluorouracil (5-FU)-based chemotherapy, intraoperative irradiation, and more recently, external-beam irradiation with new systemic agents, such as gemcitabine (Gemzar).

Full Text

Duke Authors

Cited Authors

  • Czito, BG; Willett, CG; Clark, JW; Fernandez Del Castillo, C

Published Date

  • November 2000

Published In

Volume / Issue

  • 14 / 11

Start / End Page

  • 1535 - 1545

PubMed ID

  • 11125940

Pubmed Central ID

  • 11125940

International Standard Serial Number (ISSN)

  • 0890-9091


  • eng

Conference Location

  • United States