Differentiation of erythroleukemia cells in vitro: properties of chemical inducers.

Journal Article (Journal Article)

Murine erythroleukemia cells growing in vitro can be induced to differentiate. The physical properties of chemical inducers has been defined and has permitted the recognition of a variety of potent inducers. The compounds can be linear, branched, or aromatic molecules. Some are methylated. All are low molecular weight basic compounds which are hydrophylic and are potent cryoprotective agents. The inducing effects of combinations of some agents are synergistic while others are additive. These observations will permit a rational search for inducing agents with increased potency and decreased toxicity.

Full Text

Duke Authors

Cited Authors

  • Preisler, HD; Lyman, G

Published Date

  • June 1, 1975

Published In

Volume / Issue

  • 4 / 3

Start / End Page

  • 179 - 185

PubMed ID

  • 1056810

International Standard Serial Number (ISSN)

  • 0045-6039

Digital Object Identifier (DOI)

  • 10.1016/0045-6039(75)90039-1


  • eng

Conference Location

  • Ireland