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2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practice guideline.

Publication ,  Journal Article
Smith, TJ; Khatcheressian, J; Lyman, GH; Ozer, H; Armitage, JO; Balducci, L; Bennett, CL; Cantor, SB; Crawford, J; Cross, SJ; Demetri, G ...
Published in: J Clin Oncol
July 1, 2006

PURPOSE: To update the 2000 American Society of Clinical Oncology guideline on the use of hematopoietic colony-stimulating factors (CSF). UPDATE METHODOLOGY: The Update Committee completed a review and analysis of pertinent data published from 1999 through September 2005. Guided by the 1996 ASCO clinical outcomes criteria, the Update Committee formulated recommendations based on improvements in survival, quality of life, toxicity reduction and cost-effectiveness. RECOMMENDATIONS: The 2005 Update Committee agreed unanimously that reduction in febrile neutropenia (FN) is an important clinical outcome that justifies the use of CSFs, regardless of impact on other factors, when the risk of FN is approximately 20% and no other equally effective regimen that does not require CSFs is available. Primary prophylaxis is recommended for the prevention of FN in patients who are at high risk based on age, medical history, disease characteristics, and myelotoxicity of the chemotherapy regimen. CSF use allows a modest to moderate increase in dose-density and/or dose-intensity of chemotherapy regimens. Dose-dense regimens should only be used within an appropriately designed clinical trial or if supported by convincing efficacy data. Prophylactic CSF for patients with diffuse aggressive lymphoma aged 65 years and older treated with curative chemotherapy (CHOP or more aggressive regimens) should be given to reduce the incidence of FN and infections. Current recommendations for the management of patients exposed to lethal doses of total body radiotherapy, but not doses high enough to lead to certain death due to injury to other organs, includes the prompt administration of CSF or pegylated G-CSF.

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Published In

J Clin Oncol

DOI

EISSN

1527-7755

Publication Date

July 1, 2006

Volume

24

Issue

19

Start / End Page

3187 / 3205

Location

United States

Related Subject Headings

  • Survival Analysis
  • Stem Cell Transplantation
  • Risk Factors
  • Quality of Life
  • Patient Selection
  • Oncology & Carcinogenesis
  • Neutropenia
  • Neoplasms
  • Leukemia, Myeloid, Acute
  • Humans
 

Citation

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Smith, T. J., Khatcheressian, J., Lyman, G. H., Ozer, H., Armitage, J. O., Balducci, L., … Wolff, A. C. (2006). 2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practice guideline. J Clin Oncol, 24(19), 3187–3205. https://doi.org/10.1200/JCO.2006.06.4451
Smith, Thomas J., James Khatcheressian, Gary H. Lyman, Howard Ozer, James O. Armitage, Lodovico Balducci, Charles L. Bennett, et al. “2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practice guideline.J Clin Oncol 24, no. 19 (July 1, 2006): 3187–3205. https://doi.org/10.1200/JCO.2006.06.4451.
Smith TJ, Khatcheressian J, Lyman GH, Ozer H, Armitage JO, Balducci L, et al. 2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practice guideline. J Clin Oncol. 2006 Jul 1;24(19):3187–205.
Smith, Thomas J., et al. “2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practice guideline.J Clin Oncol, vol. 24, no. 19, July 2006, pp. 3187–205. Pubmed, doi:10.1200/JCO.2006.06.4451.
Smith TJ, Khatcheressian J, Lyman GH, Ozer H, Armitage JO, Balducci L, Bennett CL, Cantor SB, Crawford J, Cross SJ, Demetri G, Desch CE, Pizzo PA, Schiffer CA, Schwartzberg L, Somerfield MR, Somlo G, Wade JC, Wade JL, Winn RJ, Wozniak AJ, Wolff AC. 2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practice guideline. J Clin Oncol. 2006 Jul 1;24(19):3187–3205.

Published In

J Clin Oncol

DOI

EISSN

1527-7755

Publication Date

July 1, 2006

Volume

24

Issue

19

Start / End Page

3187 / 3205

Location

United States

Related Subject Headings

  • Survival Analysis
  • Stem Cell Transplantation
  • Risk Factors
  • Quality of Life
  • Patient Selection
  • Oncology & Carcinogenesis
  • Neutropenia
  • Neoplasms
  • Leukemia, Myeloid, Acute
  • Humans