An infant with homozygous hemoglobin D-Iran.

Published

Journal Article

Hemoglobin D-Iran (Hb D-Iran, beta 22 Glu-->Gln) is a beta-chain variant that was first described in 1973. Hb D-Iran in combination with normal Hb A (Hb D-Iran trait) is a benign condition. Hb D-Iran has also been described in combination with sickle hemoglobin and beta thalassemia, but never as a homozygous mutation. The authors describe a case of homozygous Hb D-Iran in an infant of Pakistani descent. The hematologic values, hemoglobin electrophoresis, peripheral blood smear, and clinical course to date suggest that homozygous Hb D-Iran is a relatively benign condition with mild microcytic anemia, poikilocytosis, and minimal hemolysis.

Full Text

Cited Authors

  • Thornburg, CD; Zimmerman, SA; Schultz, WH; Ware, RE

Published Date

  • January 2001

Published In

Volume / Issue

  • 23 / 1

Start / End Page

  • 67 - 68

PubMed ID

  • 11196276

Pubmed Central ID

  • 11196276

Electronic International Standard Serial Number (EISSN)

  • 1536-3678

International Standard Serial Number (ISSN)

  • 1077-4114

Digital Object Identifier (DOI)

  • 10.1097/00043426-200101000-00017

Language

  • eng