Effects of unsteady state conditions on the biooxidation of methyl ethyl and methyl isobutyl ketone in continuous flow liquid phase cultures

Journal Article

The effects of changing operating conditions on the biooxidation of methyl ethyl and/or methyl isobutyl ketone in continuous flow enrichment culture are examined. Particular emphasis is placed on responses to step changes in feed stream concentrations and to substrate pulses injected directly into the culture supernatant. In general, the enrichment culture was better able to handle transients involving methyl isobutyl ketone, the preferred carbon substrate. However, the highly complex response patterns observed clearly indicated major gaps in knowledge concerning the physiology of methyl ketone-oxidizing bacteria. In spite of the two carbon substrates investigated being major environmental pollutants, their removal in waste biotreatment processes is remarkably little understood.

Full Text

Duke Authors

Cited Authors

  • Geoghegan, DP; Hamer, G; Deshusses, MA

Published Date

  • January 1, 1997

Published In

Volume / Issue

  • 16 / 6

Start / End Page

  • 315 - 322

International Standard Serial Number (ISSN)

  • 0178-515X

Digital Object Identifier (DOI)

  • 10.1007/s004490050329

Citation Source

  • Scopus