A PCR-RFLP typing method for adhesion molecule gene polymorphisms and allele frequencies in a normal UK population.
We report simple and reproducible PCR-RFLP typing methods for the polymorphisms in the ICAM-1, E-selectin and PECAM-1 genes. The genotype and allele frequencies detected in a normal UK population did not deviate significantly from the Hardy-Weinberg equilibrium; neither did they differ from frequencies previously reported using SSP or SSCP methods.
Gbadegesin, RA; Watson, CJ; Cotton, SA; Brenchley, PEC; Webb, NJA
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