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Hepatitis B antigen in saliva, urine, and stool.

Publication ,  Journal Article
Irwin, GR; Allen, AM; Bancroft, WH; Karwacki, JJ; Brown, HL; Pinkerton, RH; Willhight, M; Top, FH
Published in: Infect Immun
January 1975

A survey of hepatitis B patients, asymptomatic hepatitis B antigen (HBsAg) carriers, and control subjects was conducted to determine the relationship between antigenemia and antigen excretion in saliva, urine, and stool. Radioimmunoassay was used to detect HBsAg. Specificity-confirmed HBsAg was detected in the saliva of 6 (30%) of 20 antigenemic patients, 1 (5%) of 20 nonantigenemic patients, 14 (34%) of 41 carriers, and 0 of 112 controls. HBsAg was detected in urine only after 100-fold concentration of first-morning specimens. Specificity-confirmed HBsAg was present in the urine of 7 (16%) of 43 carriers; unconfirmed HBsAg was found in the urine of 5 (13%) of 38 patients and 5 (5%) of 112 controls. Unconfirmed HBsAg was detected in concentrated stool specimens from 5 (46%) of 11 patients and 3 of 8 carriers and controls. Longitudinally collected specimens from antigenemic subjects showed no consistent patterns of antigen excretion.

Duke Scholars

Published In

Infect Immun

DOI

ISSN

0019-9567

Publication Date

January 1975

Volume

11

Issue

1

Start / End Page

142 / 145

Location

United States

Related Subject Headings

  • Urine
  • Saliva
  • Radioimmunoassay
  • Microbiology
  • Hepatitis B Antigens
  • Hepatitis B
  • Filtration
  • Feces
  • Carrier State
  • 3207 Medical microbiology
 

Citation

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MLA
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Irwin, G. R., Allen, A. M., Bancroft, W. H., Karwacki, J. J., Brown, H. L., Pinkerton, R. H., … Top, F. H. (1975). Hepatitis B antigen in saliva, urine, and stool. Infect Immun, 11(1), 142–145. https://doi.org/10.1128/iai.11.1.142-145.1975
Irwin, G. R., A. M. Allen, W. H. Bancroft, J. J. Karwacki, H. L. Brown, R. H. Pinkerton, M. Willhight, and F. H. Top. “Hepatitis B antigen in saliva, urine, and stool.Infect Immun 11, no. 1 (January 1975): 142–45. https://doi.org/10.1128/iai.11.1.142-145.1975.
Irwin GR, Allen AM, Bancroft WH, Karwacki JJ, Brown HL, Pinkerton RH, et al. Hepatitis B antigen in saliva, urine, and stool. Infect Immun. 1975 Jan;11(1):142–5.
Irwin, G. R., et al. “Hepatitis B antigen in saliva, urine, and stool.Infect Immun, vol. 11, no. 1, Jan. 1975, pp. 142–45. Pubmed, doi:10.1128/iai.11.1.142-145.1975.
Irwin GR, Allen AM, Bancroft WH, Karwacki JJ, Brown HL, Pinkerton RH, Willhight M, Top FH. Hepatitis B antigen in saliva, urine, and stool. Infect Immun. 1975 Jan;11(1):142–145.

Published In

Infect Immun

DOI

ISSN

0019-9567

Publication Date

January 1975

Volume

11

Issue

1

Start / End Page

142 / 145

Location

United States

Related Subject Headings

  • Urine
  • Saliva
  • Radioimmunoassay
  • Microbiology
  • Hepatitis B Antigens
  • Hepatitis B
  • Filtration
  • Feces
  • Carrier State
  • 3207 Medical microbiology