Hepatitis B antigen in saliva, urine, and stool.
Journal Article
A survey of hepatitis B patients, asymptomatic hepatitis B antigen (HBsAg) carriers, and control subjects was conducted to determine the relationship between antigenemia and antigen excretion in saliva, urine, and stool. Radioimmunoassay was used to detect HBsAg. Specificity-confirmed HBsAg was detected in the saliva of 6 (30%) of 20 antigenemic patients, 1 (5%) of 20 nonantigenemic patients, 14 (34%) of 41 carriers, and 0 of 112 controls. HBsAg was detected in urine only after 100-fold concentration of first-morning specimens. Specificity-confirmed HBsAg was present in the urine of 7 (16%) of 43 carriers; unconfirmed HBsAg was found in the urine of 5 (13%) of 38 patients and 5 (5%) of 112 controls. Unconfirmed HBsAg was detected in concentrated stool specimens from 5 (46%) of 11 patients and 3 of 8 carriers and controls. Longitudinally collected specimens from antigenemic subjects showed no consistent patterns of antigen excretion.
Full Text
Duke Authors
Cited Authors
- Irwin, GR; Allen, AM; Bancroft, WH; Karwacki, JJ; Brown, HL; Pinkerton, RH; Willhight, M; Top, FH
Published Date
- January 1975
Published In
Volume / Issue
- 11 / 1
Start / End Page
- 142 - 145
PubMed ID
- 1116873
Pubmed Central ID
- 1116873
International Standard Serial Number (ISSN)
- 0019-9567
Digital Object Identifier (DOI)
- 10.1128/IAI.11.1.142-145.1975
Language
- eng
Conference Location
- United States