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Cystine-glutamate transport interactions in rat renal cortical tubules, brushborder vesicles, and cultured renal tubule cells.

Publication ,  Journal Article
Foreman, JW; McNamara, PD; Bowring, MA; Lee, J; Rea, C; Segal, S
Published in: Biosci Rep
January 1986

Glutamate had no significant effect on the uptake of 0.025 mM cystine by isolated rat renal cortical tubules and brushborder membrane vesicles in contrast to lysine which significantly inhibits cystine transport. Glutamate, however, markedly inhibited cystine uptake by rat renal tubule cells grown in a serum-free, hormonally defined media for 5 days. Lysine also inhibited cystine transport in these cultured renal tubule cells.

Duke Scholars

Published In

Biosci Rep

DOI

ISSN

0144-8463

Publication Date

January 1986

Volume

6

Issue

1

Start / End Page

113 / 119

Location

England

Related Subject Headings

  • Rats, Inbred Strains
  • Rats
  • Microvilli
  • Male
  • Lysine
  • Kidney Tubules
  • Kidney Cortex
  • Glutamic Acid
  • Glutamates
  • Drug Interactions
 

Citation

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MLA
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Foreman, J. W., McNamara, P. D., Bowring, M. A., Lee, J., Rea, C., & Segal, S. (1986). Cystine-glutamate transport interactions in rat renal cortical tubules, brushborder vesicles, and cultured renal tubule cells. Biosci Rep, 6(1), 113–119. https://doi.org/10.1007/BF01145186
Foreman, J. W., P. D. McNamara, M. A. Bowring, J. Lee, C. Rea, and S. Segal. “Cystine-glutamate transport interactions in rat renal cortical tubules, brushborder vesicles, and cultured renal tubule cells.Biosci Rep 6, no. 1 (January 1986): 113–19. https://doi.org/10.1007/BF01145186.
Foreman JW, McNamara PD, Bowring MA, Lee J, Rea C, Segal S. Cystine-glutamate transport interactions in rat renal cortical tubules, brushborder vesicles, and cultured renal tubule cells. Biosci Rep. 1986 Jan;6(1):113–9.
Foreman, J. W., et al. “Cystine-glutamate transport interactions in rat renal cortical tubules, brushborder vesicles, and cultured renal tubule cells.Biosci Rep, vol. 6, no. 1, Jan. 1986, pp. 113–19. Pubmed, doi:10.1007/BF01145186.
Foreman JW, McNamara PD, Bowring MA, Lee J, Rea C, Segal S. Cystine-glutamate transport interactions in rat renal cortical tubules, brushborder vesicles, and cultured renal tubule cells. Biosci Rep. 1986 Jan;6(1):113–119.
Journal cover image

Published In

Biosci Rep

DOI

ISSN

0144-8463

Publication Date

January 1986

Volume

6

Issue

1

Start / End Page

113 / 119

Location

England

Related Subject Headings

  • Rats, Inbred Strains
  • Rats
  • Microvilli
  • Male
  • Lysine
  • Kidney Tubules
  • Kidney Cortex
  • Glutamic Acid
  • Glutamates
  • Drug Interactions