Cystine-glutamate transport interactions in rat renal cortical tubules, brushborder vesicles, and cultured renal tubule cells.

Journal Article (Journal Article)

Glutamate had no significant effect on the uptake of 0.025 mM cystine by isolated rat renal cortical tubules and brushborder membrane vesicles in contrast to lysine which significantly inhibits cystine transport. Glutamate, however, markedly inhibited cystine uptake by rat renal tubule cells grown in a serum-free, hormonally defined media for 5 days. Lysine also inhibited cystine transport in these cultured renal tubule cells.

Full Text

Duke Authors

Cited Authors

  • Foreman, JW; McNamara, PD; Bowring, MA; Lee, J; Rea, C; Segal, S

Published Date

  • January 1, 1986

Published In

Volume / Issue

  • 6 / 1

Start / End Page

  • 113 - 119

PubMed ID

  • 2870746

International Standard Serial Number (ISSN)

  • 0144-8463

Digital Object Identifier (DOI)

  • 10.1007/BF01145186


  • eng

Conference Location

  • England