Uptake of proline by brushborder vesicles isolated from human kidney cortex.

Journal Article (Journal Article)

Proline transport into renal brushborder membrane vesicles isolated from human kidney is mediated by two uptake systems. The high-affinity system is stimulated by a Na gradient and appears to be shared with glycine while the low-affinity system is not. Uptake curves of low concentrations of proline exhibit a Na-gradient-dependent overshoot indicative of electrogenic transport. The proline transport systems observed in isolated human renal brushborder membrane vesicles appear to have characteristics similar to those in rat kidney membranes.

Full Text

Duke Authors

Cited Authors

  • Foreman, JW; McNamara, PD; Pepe, LM; Ginkinger, K; Segal, S

Published Date

  • December 1985

Published In

Volume / Issue

  • 34 / 3

Start / End Page

  • 304 - 309

PubMed ID

  • 4096719

International Standard Serial Number (ISSN)

  • 0006-2944

Digital Object Identifier (DOI)

  • 10.1016/0006-2944(85)90092-4


  • eng

Conference Location

  • United States