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Uptake of proline by brushborder vesicles isolated from human kidney cortex.

Publication ,  Journal Article
Foreman, JW; McNamara, PD; Pepe, LM; Ginkinger, K; Segal, S
Published in: Biochem Med
December 1985

Proline transport into renal brushborder membrane vesicles isolated from human kidney is mediated by two uptake systems. The high-affinity system is stimulated by a Na gradient and appears to be shared with glycine while the low-affinity system is not. Uptake curves of low concentrations of proline exhibit a Na-gradient-dependent overshoot indicative of electrogenic transport. The proline transport systems observed in isolated human renal brushborder membrane vesicles appear to have characteristics similar to those in rat kidney membranes.

Duke Scholars

Published In

Biochem Med

DOI

ISSN

0006-2944

Publication Date

December 1985

Volume

34

Issue

3

Start / End Page

304 / 309

Location

United States

Related Subject Headings

  • Proline
  • Microvilli
  • Kinetics
  • Kidney Tubules, Proximal
  • Kidney Cortex
  • In Vitro Techniques
  • Hydroxyproline
  • Humans
  • Glycine
  • Alanine
 

Citation

APA
Chicago
ICMJE
MLA
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Foreman, J. W., McNamara, P. D., Pepe, L. M., Ginkinger, K., & Segal, S. (1985). Uptake of proline by brushborder vesicles isolated from human kidney cortex. Biochem Med, 34(3), 304–309. https://doi.org/10.1016/0006-2944(85)90092-4
Foreman, J. W., P. D. McNamara, L. M. Pepe, K. Ginkinger, and S. Segal. “Uptake of proline by brushborder vesicles isolated from human kidney cortex.Biochem Med 34, no. 3 (December 1985): 304–9. https://doi.org/10.1016/0006-2944(85)90092-4.
Foreman JW, McNamara PD, Pepe LM, Ginkinger K, Segal S. Uptake of proline by brushborder vesicles isolated from human kidney cortex. Biochem Med. 1985 Dec;34(3):304–9.
Foreman, J. W., et al. “Uptake of proline by brushborder vesicles isolated from human kidney cortex.Biochem Med, vol. 34, no. 3, Dec. 1985, pp. 304–09. Pubmed, doi:10.1016/0006-2944(85)90092-4.
Foreman JW, McNamara PD, Pepe LM, Ginkinger K, Segal S. Uptake of proline by brushborder vesicles isolated from human kidney cortex. Biochem Med. 1985 Dec;34(3):304–309.

Published In

Biochem Med

DOI

ISSN

0006-2944

Publication Date

December 1985

Volume

34

Issue

3

Start / End Page

304 / 309

Location

United States

Related Subject Headings

  • Proline
  • Microvilli
  • Kinetics
  • Kidney Tubules, Proximal
  • Kidney Cortex
  • In Vitro Techniques
  • Hydroxyproline
  • Humans
  • Glycine
  • Alanine