Developmental outcome of very low birth weight infants as a function of biological risk and psychosocial risk.

Journal Article (Journal Article)

The relative contribution of biological and psychosocial risk factors to developmental outcome of 102 very low birth weight infants (< 1500 g) was delineated through 24 months corrected age. Biological risk, assessed by the Neurobiologic Risk Score (NBRS), accounted for significant amounts of variance in Bayley Mental Developmental Index (MDI) and Psychomotor Developmental Index (PDI) at the 6-, 15-, and 24-month assessment points. Psychosocial risk, reflected in maternal appraisals of daily stress, accounted for a significant increment in cognitive outcome (MDI), over and above that accounted for by the NBRS, at each assessment point. Cognitive functioning at each assessment point differed as a function of biological risk and psychosocial risk status. The findings are discussed in terms of maternal stress as a marker of, and salient intervention target for, caregiving environments that can maximize or minimize the effects of biological vulnerability.

Full Text

Duke Authors

Cited Authors

  • Thompson, RJ; Goldstein, RF; Oehler, JM; Gustafson, KE; Catlett, AT; Brazy, JE

Published Date

  • August 1994

Published In

Volume / Issue

  • 15 / 4

Start / End Page

  • 232 - 238

PubMed ID

  • 7798368

International Standard Serial Number (ISSN)

  • 0196-206X


  • eng

Conference Location

  • United States