Normative values for exhaled breath condensate pH and its relationship to exhaled nitric oxide in healthy African Americans.

Journal Article (Academic article)

BACKGROUND: Exhaled breath condensate (EBC) pH and exhaled nitric oxide (FeNO) have been proposed as markers of asthma severity. EBC pH values below 6.5 have been associated with asthma exacerbations. Protonation of airway nitrite occurs at low pH and may contribute to FeNO. OBJECTIVE: To establish normative EBC pH values and to determine the contribution of EBC pH to FeNO in healthy African Americans. METHODS: Two hundred seventy healthy African American subjects without asthma between 18 and 40 years old were evaluated. Subjects had simultaneous measurement of EBC pH, EBC nitrite, nitrate, and FeNO. RESULTS: The median EBC pH was 8.14 (interquartile range, 7.83-8.28). Of subjects, 11.9% had an EBC pH

Duke Authors

Cited Authors

  • Hauswirth, DW; Sundy, JS; Mervin Blake, S; Fernandez, CA; Patch, KB; Alexander, KM; Allgood, S; McNair, PD; Levesque, MC

Published Date

  • July 2008

Published In

Volume / Issue

  • 122 / 1

Start / End Page

  • 101 - 106

PubMed ID

  • 18472151

International Standard Serial Number (ISSN)

  • 1097-6825

Conference Location

  • united states