Rolandic encephalopathy and epilepsia partialis continua following bone marrow transplant.


Journal Article

Epilepsia partialis continua (EPC) is a condition defined by prolonged focal myoclonus. Often resistant to therapy, EPC in children is frequently present in Rasmussen encephalitis, a form of chronic encephalitis of uncertain etiology. We discuss a child who developed bilateral EPC 5 months after a bone marrow transplant. Neuroimaging studies showed signal abnormalities on both sensory-motor areas. An extensive search failed to reveal the etiology of the disorder, but treatment with a broad-spectrum anti-viral agent was associated with resolution of the process. An unidentified infectious agent may be responsible for an encephalitis of the motor strip in immunosuppressed patients.

Full Text

Duke Authors

Cited Authors

  • Antunes, NL; Boulad, F; Prasad, V; Rosenblum, M; Lis, E; Souweidane, M

Published Date

  • October 2000

Published In

Volume / Issue

  • 26 / 8

Start / End Page

  • 917 - 919

PubMed ID

  • 11081396

Pubmed Central ID

  • 11081396

International Standard Serial Number (ISSN)

  • 0268-3369

Digital Object Identifier (DOI)

  • 10.1038/sj.bmt.1702637


  • eng

Conference Location

  • England