The pathogenesis of insulin resistance in children: metabolic complications and the roles of diet, exercise and pharmacotherapy in the prevention of type 2 diabetes.

Journal Article (Review)

In this manuscript we discuss the pathogenesis of type 2 diabetes in children, emphasizing the central importance of obesity, insulin resistance, dyslipidemia, hypertension and endothelial dysfunction. We then review critically the benefits of diet, exercise and pharmacotherapy in preventing type 2 diabetes and vascular complications in high risk children and young adults.

Full Text

Duke Authors

Cited Authors

  • Artz, E; Freemark, M

Published Date

  • March 2004

Published In

Volume / Issue

  • 1 / 3

Start / End Page

  • 296 - 309

PubMed ID

  • 16437023

International Standard Serial Number (ISSN)

  • 1565-4753

Language

  • eng

Conference Location

  • Israel