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A review of the physical and chemical properties of human semen and the formulation of a semen simulant.

Publication ,  Journal Article
Owen, DH; Katz, DF
Published in: Journal of andrology
July 2005

A fluid medium was developed to simulate the salient physical and chemical properties of human semen. The composition of the medium was based upon an extensive review of the literature on constituents of human semen. In choosing the ingredients for this medium, the goal was to emphasize properties that influence interactions of human semen with topical contraceptive, prophylactic, or therapeutic products. Among these properties, pH and buffering capacity, osmolarity, ionic strength, and rheological properties play dominant roles in the physico-chemical processes that govern drug release kinetics and delivery vehicle distribution.

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Published In

Journal of andrology

DOI

EISSN

1939-4640

ISSN

0196-3635

Publication Date

July 2005

Volume

26

Issue

4

Start / End Page

459 / 469

Related Subject Headings

  • Semen
  • Obstetrics & Reproductive Medicine
  • Male
  • Humans
  • Culture Media
  • 1114 Paediatrics and Reproductive Medicine
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Owen, D. H., & Katz, D. F. (2005). A review of the physical and chemical properties of human semen and the formulation of a semen simulant. Journal of Andrology, 26(4), 459–469. https://doi.org/10.2164/jandrol.04104
Owen, Derek H., and David F. Katz. “A review of the physical and chemical properties of human semen and the formulation of a semen simulant.Journal of Andrology 26, no. 4 (July 2005): 459–69. https://doi.org/10.2164/jandrol.04104.
Owen, Derek H., and David F. Katz. “A review of the physical and chemical properties of human semen and the formulation of a semen simulant.Journal of Andrology, vol. 26, no. 4, July 2005, pp. 459–69. Epmc, doi:10.2164/jandrol.04104.
Journal cover image

Published In

Journal of andrology

DOI

EISSN

1939-4640

ISSN

0196-3635

Publication Date

July 2005

Volume

26

Issue

4

Start / End Page

459 / 469

Related Subject Headings

  • Semen
  • Obstetrics & Reproductive Medicine
  • Male
  • Humans
  • Culture Media
  • 1114 Paediatrics and Reproductive Medicine
  • 1103 Clinical Sciences