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A model of cortical window healing in the rabbit.

Publication ,  Journal Article
Fyda, TM; Callaghan, JJ; Fulghum, CS; Seaber, AV; Myers, BS
Published in: Orthopedics
February 1995

A rabbit femur cortical window model was developed to study the time-dependent mechanical and radiographic changes with various treatments of surgically created windows. In the present experiment the time-dependent differences in torsional whole bone strength between femora treated with window replacement and those treated without replacement were evaluated. The 3.175 mm diameter windows were surgically created with a power trephine at the lateral femoral isthmus unilaterally, with the contralateral femur serving as a paired control. In one group of animals the window was reconstructed by replacement of the excised cortical plug while in the other group the window was left unreplaced. Each group was divided into three subgroups sacrificed at 3, 6, and 9 weeks postoperatively. Lateral radiographs were obtained immediately prior to sacrifice. After sacrifice bilateral femora were harvested and loaded to failure on a torsional testing apparatus to obtain values for ultimate torque, maximum angle of deformation, and energy capacity expressed as percent of paired control. Replacement resulted in significantly greater whole bone strength (P < .041), and strength increased significantly with time (P < .006). Radiographic appearance correlated significantly with both treatment and time, but not strength. The model was sensitive to both treatment-dependent and time-dependent effects, demonstrating potential for evaluation of other cortical window treatments.

Duke Scholars

Published In

Orthopedics

DOI

EISSN

1938-2367

ISSN

0147-7447

Publication Date

February 1995

Volume

18

Issue

2

Start / End Page

177 / 184

Related Subject Headings

  • Torsion Abnormality
  • Time Factors
  • Reoperation
  • Rabbits
  • Orthopedics
  • Hip Prosthesis
  • Fracture Healing
  • Femur
  • Bone Regeneration
  • Biomechanical Phenomena
 

Citation

APA
Chicago
ICMJE
MLA
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Fyda, T. M., Callaghan, J. J., Fulghum, C. S., Seaber, A. V., & Myers, B. S. (1995). A model of cortical window healing in the rabbit. Orthopedics, 18(2), 177–184. https://doi.org/10.3928/0147-7447-19950201-16
Fyda, T. M., J. J. Callaghan, C. S. Fulghum, A. V. Seaber, and B. S. Myers. “A model of cortical window healing in the rabbit.Orthopedics 18, no. 2 (February 1995): 177–84. https://doi.org/10.3928/0147-7447-19950201-16.
Fyda TM, Callaghan JJ, Fulghum CS, Seaber AV, Myers BS. A model of cortical window healing in the rabbit. Orthopedics. 1995 Feb;18(2):177–84.
Fyda, T. M., et al. “A model of cortical window healing in the rabbit.Orthopedics, vol. 18, no. 2, Feb. 1995, pp. 177–84. Epmc, doi:10.3928/0147-7447-19950201-16.
Fyda TM, Callaghan JJ, Fulghum CS, Seaber AV, Myers BS. A model of cortical window healing in the rabbit. Orthopedics. 1995 Feb;18(2):177–184.

Published In

Orthopedics

DOI

EISSN

1938-2367

ISSN

0147-7447

Publication Date

February 1995

Volume

18

Issue

2

Start / End Page

177 / 184

Related Subject Headings

  • Torsion Abnormality
  • Time Factors
  • Reoperation
  • Rabbits
  • Orthopedics
  • Hip Prosthesis
  • Fracture Healing
  • Femur
  • Bone Regeneration
  • Biomechanical Phenomena