Diagnostic challenge in recurrent skin rash after autologous bone marrow transplantation.


Journal Article

Engraftment syndrome, autologous graft-versus-host disease (GVHD), and infection after autologous hematopoietic cell transplantation can have similar clinical presentations. Here, we describe a patient with refractory Ewing sarcoma who had recurrent skin rash after autologous hematopoietic cell transplantation. Although the rash was diagnosed as GVHD histologically, this case illustrates the diagnostic dilemma of distinguishing engraftment syndrome, autologous GVHD, or concomitant viral infection. Because therapy for these entities is different, distinguishing them is important. Establishment of diagnostic criteria and understanding of the pathophysiology of these entities may lead to better management and to improved therapy of refractory cancer.

Full Text

Duke Authors

Cited Authors

  • Inaba, H; Hale, G; Leung, W; Woodard, P; Burnette, K; Handgretinger, R; Barfield, R

Published Date

  • August 2006

Published In

Volume / Issue

  • 28 / 8

Start / End Page

  • 525 - 528

PubMed ID

  • 16912592

Pubmed Central ID

  • 16912592

International Standard Serial Number (ISSN)

  • 1077-4114

Digital Object Identifier (DOI)

  • 10.1097/01.mph.0000212966.60383.74


  • eng

Conference Location

  • United States