Aripiprazole for agitation in a 13-year-old girl with neuroleptic malignant syndrome.

Journal Article (Journal Article)

UNLABELLED: Neuroleptic Malignant Syndrome (NMS) rarely results from atypical antipsychotic therapy. To date, no information is available on the incidence of NMS with aripiprazole, a newer neuroleptic. OBJECTIVE: To examine the results of a trial of aripiprazole administered to a 13-year-old Mexican-American girl during the course of NMS. METHODS: Vital signs and laboratory values obtained before and during the aripiprazole trial were compared. RESULTS: Aripiprazole administration resulted in a mild increase in tachycardia and brief worsening of serum creatinine kinase level, but did not significantly affect temperature, respiratory rate, or blood pressure. CONCLUSIONS: In this adolescent with NMS, aripiprazole treatment was associated with a mild worsening of symptoms.

Full Text

Duke Authors

Cited Authors

  • Dew, RE; Rosenquist, PB; McCall, WV

Published Date

  • April 2005

Published In

Volume / Issue

  • 17 / 2

Start / End Page

  • 187 - 188

PubMed ID

  • 15971738

International Standard Serial Number (ISSN)

  • 0334-0139

Digital Object Identifier (DOI)

  • 10.1515/ijamh.2005.17.2.187


  • eng

Conference Location

  • Germany