Comparison of fMRI and PEPSI during language processing in children.


Journal Article

The present study explored the correlation between lactate as detected by MR spectroscopy (MRS) and blood oxygenation level dependent (BOLD) responses in male children during auditory-based language tasks. All subjects (N = 8) participated in one proton echo planar spectroscopic imaging (PEPSI) and one functional magnetic resonance imaging (fMRI) session that required phonological and lexical judgments to aurally presented stimuli. Valid PEPSI data was limited in the frontal areas of the brain due to the magnetic susceptibility of the eye orbits and frontal sinuses. Findings from the remainder of the brain indicate that subjects show a significant consistency across imaging techniques in the left temporal area during the lexical task, but not in any other measurable area or during the phonological task. Magn Reson Med 45:217-225, 2001.

Full Text

Cited Authors

  • Serafini, S; Steury, K; Richards, T; Corina, D; Abbott, R; Dager, SR; Berninger, V

Published Date

  • February 2001

Published In

Volume / Issue

  • 45 / 2

Start / End Page

  • 217 - 225

PubMed ID

  • 11180429

Pubmed Central ID

  • 11180429

Electronic International Standard Serial Number (EISSN)

  • 1522-2594

International Standard Serial Number (ISSN)

  • 0740-3194

Digital Object Identifier (DOI)

  • 10.1002/1522-2594(200102)45:2<217::aid-mrm1030>;2-3


  • eng