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Project PREVENT: a randomized trial to reduce multiple behavioral risk factors for colon cancer.

Publication ,  Journal Article
Emmons, KM; McBride, CM; Puleo, E; Pollak, KI; Clipp, E; Kuntz, K; Marcus, BH; Napolitano, M; Onken, J; Farraye, F; Fletcher, R
Published in: Cancer Epidemiol Biomarkers Prev
June 2005

BACKGROUND: This report examines the outcome data for Project PREVENT, a two-site randomized control trial designed to reduce behavioral risk factors for colorectal cancer among individuals who have been diagnosed with adenomatous colon polyps. METHODS: The study sample included 1,247 patients with recent diagnosis of adenomatous colorectal polyps. Within 4 weeks following the polypectomy, participants completed a baseline survey by telephone, and were randomized to either Usual Care (UC) or the PREVENT intervention, which was designed to target multiple risk factors. The intervention consisted of a telephone-delivered intervention plus tailored materials, and focused on the six primary behavioral risk factors for colorectal cancer, including red meat consumption, fruit and vegetable intake, multivitamin intake, alcohol, smoking, and physical inactivity. RESULTS: Participation in the PREVENT intervention was associated with a significantly greater reduction in prevalence of multiple risk factors for colorectal cancer compared with UC. Only about one third of UC participants dropped any risk factors during the study period, compared with almost half of the PREVENT participants. PREVENT participants were also significantly more likely to change more than one behavior than UC participants. CONCLUSIONS: The PREVENT intervention was effective in helping patients change multiple risk factors. These results provide further support that more comprehensive interventions that move beyond emphasis on a single risk factor are acceptable to patient populations, can result in improvements, and are cost effective.

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Published In

Cancer Epidemiol Biomarkers Prev

DOI

ISSN

1055-9965

Publication Date

June 2005

Volume

14

Issue

6

Start / End Page

1453 / 1459

Location

United States

Related Subject Headings

  • Telephone
  • Smoking
  • Risk Factors
  • Middle Aged
  • Male
  • Humans
  • Health Behavior
  • Female
  • Exercise
  • Epidemiology
 

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Emmons, K. M., McBride, C. M., Puleo, E., Pollak, K. I., Clipp, E., Kuntz, K., … Fletcher, R. (2005). Project PREVENT: a randomized trial to reduce multiple behavioral risk factors for colon cancer. Cancer Epidemiol Biomarkers Prev, 14(6), 1453–1459. https://doi.org/10.1158/1055-9965.EPI-04-0620
Emmons, Karen M., Colleen M. McBride, Elaine Puleo, Kathryn I. Pollak, Elizabeth Clipp, Karen Kuntz, Bess H. Marcus, et al. “Project PREVENT: a randomized trial to reduce multiple behavioral risk factors for colon cancer.Cancer Epidemiol Biomarkers Prev 14, no. 6 (June 2005): 1453–59. https://doi.org/10.1158/1055-9965.EPI-04-0620.
Emmons KM, McBride CM, Puleo E, Pollak KI, Clipp E, Kuntz K, et al. Project PREVENT: a randomized trial to reduce multiple behavioral risk factors for colon cancer. Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1453–9.
Emmons, Karen M., et al. “Project PREVENT: a randomized trial to reduce multiple behavioral risk factors for colon cancer.Cancer Epidemiol Biomarkers Prev, vol. 14, no. 6, June 2005, pp. 1453–59. Pubmed, doi:10.1158/1055-9965.EPI-04-0620.
Emmons KM, McBride CM, Puleo E, Pollak KI, Clipp E, Kuntz K, Marcus BH, Napolitano M, Onken J, Farraye F, Fletcher R. Project PREVENT: a randomized trial to reduce multiple behavioral risk factors for colon cancer. Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1453–1459.

Published In

Cancer Epidemiol Biomarkers Prev

DOI

ISSN

1055-9965

Publication Date

June 2005

Volume

14

Issue

6

Start / End Page

1453 / 1459

Location

United States

Related Subject Headings

  • Telephone
  • Smoking
  • Risk Factors
  • Middle Aged
  • Male
  • Humans
  • Health Behavior
  • Female
  • Exercise
  • Epidemiology