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Acute Budd-Chiari syndrome during pregnancy: surgical treatment and orthotopic liver transplantation with successful completion of the pregnancy.

Publication ,  Journal Article
Grant, WJ; McCashland, T; Botha, JF; Shaw, BW; Sudan, DL; Mejia, A; Iyer, K; Langnas, AN
Published in: Liver Transpl
September 2003

A 26-year-old woman presented with acute Budd-Chiari syndrome 18 weeks into a pregnancy. She was found to be heterozygous for the G20210A prothrombin gene mutation. She was treated with portacaval shunt placement and successfully completed the pregnancy, with a healthy baby delivered at 31 weeks' gestation. She developed progressive liver failure after delivery of the child, likely associated with clotting of the shunt, which occurred in the face of full anticoagulation. The patient subsequently underwent a technically complicated orthotopic liver transplantation, but died 10 months after transplantation. This case illustrates the challenges involved in the treatment of Budd-Chiari syndrome, in addition to difficulties balancing the health of a mother and an unborn child. It is the only case of surgical treatment of Budd-Chiari syndrome during pregnancy reported in the literature.

Duke Scholars

Published In

Liver Transpl

DOI

ISSN

1527-6465

Publication Date

September 2003

Volume

9

Issue

9

Start / End Page

976 / 979

Location

United States

Related Subject Headings

  • Surgery
  • Pregnancy Outcome
  • Pregnancy Complications
  • Pregnancy
  • Liver Transplantation
  • Infant, Newborn
  • Humans
  • Female
  • Budd-Chiari Syndrome
  • Adult
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Grant, W. J., McCashland, T., Botha, J. F., Shaw, B. W., Sudan, D. L., Mejia, A., … Langnas, A. N. (2003). Acute Budd-Chiari syndrome during pregnancy: surgical treatment and orthotopic liver transplantation with successful completion of the pregnancy. Liver Transpl, 9(9), 976–979. https://doi.org/10.1053/jlts.2003.50134
Grant, Wendy J., Timothy McCashland, Jean F. Botha, Byers W. Shaw, Debra L. Sudan, Alejandro Mejia, Kishore Iyer, and Alan N. Langnas. “Acute Budd-Chiari syndrome during pregnancy: surgical treatment and orthotopic liver transplantation with successful completion of the pregnancy.Liver Transpl 9, no. 9 (September 2003): 976–79. https://doi.org/10.1053/jlts.2003.50134.
Grant WJ, McCashland T, Botha JF, Shaw BW, Sudan DL, Mejia A, et al. Acute Budd-Chiari syndrome during pregnancy: surgical treatment and orthotopic liver transplantation with successful completion of the pregnancy. Liver Transpl. 2003 Sep;9(9):976–9.
Grant, Wendy J., et al. “Acute Budd-Chiari syndrome during pregnancy: surgical treatment and orthotopic liver transplantation with successful completion of the pregnancy.Liver Transpl, vol. 9, no. 9, Sept. 2003, pp. 976–79. Pubmed, doi:10.1053/jlts.2003.50134.
Grant WJ, McCashland T, Botha JF, Shaw BW, Sudan DL, Mejia A, Iyer K, Langnas AN. Acute Budd-Chiari syndrome during pregnancy: surgical treatment and orthotopic liver transplantation with successful completion of the pregnancy. Liver Transpl. 2003 Sep;9(9):976–979.
Journal cover image

Published In

Liver Transpl

DOI

ISSN

1527-6465

Publication Date

September 2003

Volume

9

Issue

9

Start / End Page

976 / 979

Location

United States

Related Subject Headings

  • Surgery
  • Pregnancy Outcome
  • Pregnancy Complications
  • Pregnancy
  • Liver Transplantation
  • Infant, Newborn
  • Humans
  • Female
  • Budd-Chiari Syndrome
  • Adult