Bench reconstruction of pancreas for transplantation: experience with 192 cases.

Journal Article

UNLABELLED: Whole organ pancreaticoduodenal transplantation with bladder drainage by the duodenal segment technique is currently the preferred method of vascularized pancreas transplantation but is associated with a finite risk of surgical complications. Meticulous bench reconstruction of the pancreaticoduodenal allograft may minimize complications following transplantation. Over a 6.5-yr period, 192 pancreas transplants were performed in 181 diabetic patients by the same transplant team. A retrospective review was performed in order to describe a stepwise approach to bench preparation of the pancreaticoduodenal allograft that has developed from this experience. In this series of 192 consecutive pancreaticoduodenal reconstructions, no procured pancreas was deemed non-usable solely from an anatomic standpoint. The mean backtable pancreas preparation time was 2 h. The operative complication rate 19%, the incidence of technical graft loss was 6.8%, and there was no mortality related to technical problems. CONCLUSIONS: Using a standardized approach, meticulous bench reconstruction of the pancreaticoduodenal allograft: 1) can be performed in virtually any anatomic setting; 2) decrease complications following transplantation; 3) improves initial allograft function; and 4) minimizes organ wastage.

Full Text

Duke Authors

Cited Authors

  • Gill, IS; Sindhi, R; Jerius, JT; Sudan, D; Stratta, RJ

Published Date

  • April 1997

Published In

Volume / Issue

  • 11 / 2

Start / End Page

  • 104 - 109

PubMed ID

  • 9113445

International Standard Serial Number (ISSN)

  • 0902-0063

Language

  • eng

Conference Location

  • Denmark