Size matters (but so does time), and it's OK to be different.

Published

Journal Article

In this issue of Developmental Cell, Layalle et al. reveal new insights into how nutrition controls body size in Drosophila. Nutrition specifically affects the activity of target of rapamycin (TOR) in the prothoracic gland. Under low-nutrition conditions, TOR suppresses ecdysone secretion--which otherwise terminates larval development--thereby prolonging growth and allowing larvae to still attain a near-normal body size.

Full Text

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Duke Authors

Nijhout, H. Frederik

Cited Authors

Nijhout, HF

Published Date

October 2008

Published In

Developmental Cell

Volume / Issue

15 / 4

Start / End Page

491 - 492

PubMed ID

18854132

Pubmed Central ID

18854132

Electronic International Standard Serial Number (EISSN)

1878-1551

International Standard Serial Number (ISSN)

1534-5807

Digital Object Identifier (DOI)

10.1016/j.devcel.2008.09.014

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