Size matters (but so does time), and it's OK to be different.
Journal Article (Journal Article)
In this issue of Developmental Cell, Layalle et al. reveal new insights into how nutrition controls body size in Drosophila. Nutrition specifically affects the activity of target of rapamycin (TOR) in the prothoracic gland. Under low-nutrition conditions, TOR suppresses ecdysone secretion--which otherwise terminates larval development--thereby prolonging growth and allowing larvae to still attain a near-normal body size.
Full Text
Duke Authors
Cited Authors
- Nijhout, HF
Published Date
- October 2008
Published In
Volume / Issue
- 15 / 4
Start / End Page
- 491 - 492
PubMed ID
- 18854132
Electronic International Standard Serial Number (EISSN)
- 1878-1551
International Standard Serial Number (ISSN)
- 1534-5807
Digital Object Identifier (DOI)
- 10.1016/j.devcel.2008.09.014
Language
- eng