Size matters (but so does time), and it's OK to be different.

Journal Article (Journal Article)

In this issue of Developmental Cell, Layalle et al. reveal new insights into how nutrition controls body size in Drosophila. Nutrition specifically affects the activity of target of rapamycin (TOR) in the prothoracic gland. Under low-nutrition conditions, TOR suppresses ecdysone secretion--which otherwise terminates larval development--thereby prolonging growth and allowing larvae to still attain a near-normal body size.

Full Text

Duke Authors

Cited Authors

  • Nijhout, HF

Published Date

  • October 2008

Published In

Volume / Issue

  • 15 / 4

Start / End Page

  • 491 - 492

PubMed ID

  • 18854132

Electronic International Standard Serial Number (EISSN)

  • 1878-1551

International Standard Serial Number (ISSN)

  • 1534-5807

Digital Object Identifier (DOI)

  • 10.1016/j.devcel.2008.09.014


  • eng