Receptor-like kinase ACR4 restricts formative cell divisions in the Arabidopsis root.

Journal Article

During the development of multicellular organisms, organogenesis and pattern formation depend on formative divisions to specify and maintain pools of stem cells. In higher plants, these activities are essential to shape the final root architecture because the functioning of root apical meristems and the de novo formation of lateral roots entirely rely on it. We used transcript profiling on sorted pericycle cells undergoing lateral root initiation to identify the receptor-like kinase ACR4 of Arabidopsis as a key factor both in promoting formative cell divisions in the pericycle and in constraining the number of these divisions once organogenesis has been started. In the root tip meristem, ACR4 shows a similar action by controlling cell proliferation activity in the columella cell lineage. Thus, ACR4 function reveals a common mechanism of formative cell division control in the main root tip meristem and during lateral root initiation.

Full Text

Duke Authors

Cited Authors

  • De Smet, I; Vassileva, V; De Rybel, B; Levesque, MP; Grunewald, W; Van Damme, D; Van Noorden, G; Naudts, M; Van Isterdael, G; De Clercq, R; Wang, JY; Meuli, N; Vanneste, S; Friml, J; Hilson, P; Jürgens, G; Ingram, GC; Inzé, D; Benfey, PN; Beeckman, T

Published Date

  • October 24, 2008

Published In

Volume / Issue

  • 322 / 5901

Start / End Page

  • 594 - 597

PubMed ID

  • 18948541

Electronic International Standard Serial Number (EISSN)

  • 1095-9203

Digital Object Identifier (DOI)

  • 10.1126/science.1160158

Language

  • eng

Conference Location

  • United States