Cell identity mediates the response of Arabidopsis roots to abiotic stress.

Journal Article (Journal Article)

Little is known about the way developmental cues affect how cells interpret their environment. We characterized the transcriptional response to high salinity of different cell layers and developmental stages of the Arabidopsis root and found that transcriptional responses are highly constrained by developmental parameters. These transcriptional changes lead to the differential regulation of specific biological functions in subsets of cell layers, several of which correspond to observable physiological changes. We showed that known stress pathways primarily control semiubiquitous responses and used mutants that disrupt epidermal patterning to reveal cell-layer-specific and inter-cell-layer effects. By performing a similar analysis using iron deprivation, we identified common cell-type-specific stress responses and revealed the crucial role the environment plays in defining the transcriptional outcome of cell-fate decisions.

Full Text

Duke Authors

Cited Authors

  • Dinneny, JR; Long, TA; Wang, JY; Jung, JW; Mace, D; Pointer, S; Barron, C; Brady, SM; Schiefelbein, J; Benfey, PN

Published Date

  • May 2008

Published In

Volume / Issue

  • 320 / 5878

Start / End Page

  • 942 - 945

PubMed ID

  • 18436742

Electronic International Standard Serial Number (EISSN)

  • 1095-9203

International Standard Serial Number (ISSN)

  • 0036-8075

Digital Object Identifier (DOI)

  • 10.1126/science.1153795


  • eng