March 2000: A 16 year old female with a cerebellar mass.

Journal Article (Journal Article)

The March COM: A 16 year old female presented with headaches and cerebellar dysfunction. MR images showed a mass lesion of the right cerebellar hemisphere with mass effect on the medulla. The mass exhibited a striated pattern of alternating isointense and hypointense zones on T1-weighted images that did not contrast enhance. The lesion was hyperintense on T2-weighted images, and also showed a striated appearance. A suboccipital craniotomy and resection of the lesion was performed. Microscopically, the specimen consisted of widened folia and a disorganized cerebellar architectonic pattern in which the internal granular cell layer was occupied by a population of large dysmorphic nerve cell bodies. Patient's diagnosed with Lhermitte-Duclos disease must be adequately evaluated for Cowden's syndrome.

Full Text

Duke Authors

Cited Authors

  • Cummings, TJ; Ebert, RH; Provenzale, J; McLendon, RE

Published Date

  • July 2001

Published In

Volume / Issue

  • 11 / 3

Start / End Page

  • 391 - 393

PubMed ID

  • 11414481

International Standard Serial Number (ISSN)

  • 1015-6305


  • eng

Conference Location

  • Switzerland