Persistence of structure over fluctuations in biological electron-transfer reactions.

Journal Article (Journal Article)

In the soft-wet environment of biomolecular electron transfer, it is possible that structural fluctuations could wash out medium-specific electronic effects on electron tunneling rates. We show that beyond a transition distance (2-3 A in water and 6-7 A in proteins), fluctuation contributions to the mean-squared donor-to-acceptor tunneling matrix element are likely to dominate over the average matrix element. Even though fluctuations dominate the tunneling mechanism at larger distances, we find that the protein fold is "remembered" by the electronic coupling, and structure remains a key determinant of electron transfer kinetics.

Full Text

Duke Authors

Cited Authors

  • Balabin, IA; Beratan, DN; Skourtis, SS

Published Date

  • October 2008

Published In

Volume / Issue

  • 101 / 15

Start / End Page

  • 158102 -

PubMed ID

  • 18999647

Pubmed Central ID

  • PMC2756540

Electronic International Standard Serial Number (EISSN)

  • 1079-7114

International Standard Serial Number (ISSN)

  • 0031-9007

Digital Object Identifier (DOI)

  • 10.1103/physrevlett.101.158102

Language

  • eng