Transplantation-mediated alloimmune thrombocytopenia: Guidelines for utilization of thrombocytopenic donors.

Published

Journal Article (Review)

Transplantation-mediated alloimmune thrombocytopenia (TMAT) is donor-derived thrombocytopenia following solid-organ transplantation. To date, no clear consensus on the appropriateness of organ utilization from cadaver donors with a history of idiopathic thrombocytopenia purpura (ITP) has emerged. Herein is reported a devastating case of TMAT following liver transplantation utilizing an allograft from a donor with ITP that resulted in allograft failure. The literature is reviewed in this context to propose preliminary guidelines regarding utilization of allografts from cadaver donors with a history of ITP.

Full Text

Duke Authors

Arepally, Gowthami Morey

Cited Authors

Diaz, GC; Prowda, J; Lo, IJ; Arepally, GM; Evans, N; Wheeless, Y; Samstein, B; Guarrera, JV; Renz, JF

Published Date

December 2008

Published In

Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Volume / Issue

14 / 12

Start / End Page

1803 - 1809

PubMed ID

19025920

Pubmed Central ID

19025920

Electronic International Standard Serial Number (EISSN)

1527-6473

International Standard Serial Number (ISSN)

1527-6465

Digital Object Identifier (DOI)

10.1002/lt.21539

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