Transplantation-mediated alloimmune thrombocytopenia: Guidelines for utilization of thrombocytopenic donors.

Journal Article (Journal Article;Review)

Transplantation-mediated alloimmune thrombocytopenia (TMAT) is donor-derived thrombocytopenia following solid-organ transplantation. To date, no clear consensus on the appropriateness of organ utilization from cadaver donors with a history of idiopathic thrombocytopenia purpura (ITP) has emerged. Herein is reported a devastating case of TMAT following liver transplantation utilizing an allograft from a donor with ITP that resulted in allograft failure. The literature is reviewed in this context to propose preliminary guidelines regarding utilization of allografts from cadaver donors with a history of ITP.

Full Text

Duke Authors

Cited Authors

  • Diaz, GC; Prowda, J; Lo, IJ; Arepally, GM; Evans, N; Wheeless, Y; Samstein, B; Guarrera, JV; Renz, JF

Published Date

  • December 2008

Published In

Volume / Issue

  • 14 / 12

Start / End Page

  • 1803 - 1809

PubMed ID

  • 19025920

Electronic International Standard Serial Number (EISSN)

  • 1527-6473

Digital Object Identifier (DOI)

  • 10.1002/lt.21539

Language

  • eng

Conference Location

  • United States